G6PD deficiency disease Genetics from parents to children

A genetic disease caused by a deficiency of the enzyme G6PD (glucose-6-phosphate dehydrogenase), which is an important enzyme in various cells. throughout the body, especially red blood cells Its function is to help protect cells. from the destruction of free radicals People with this enzyme deficiency have red blood cells that break easily when exposed to various stimuli, such as certain foods, certain drugs, and infections, causing various symptoms.

Causes of G6PD deficiency

This disease is a type of hereditary disease. The recessive genes on the X chromosome (X-linked recessive) are passed on from mother to baby. This gives sons a 50 percent chance of having G6PD deficiency, and daughters a 50 percent chance of being carriers of the disease.

Symptoms of G6PD deficiency

When people with this condition are stimulated, the hemolysis of red blood cells occurs. There will be various symptoms as follows:

  • Faded skin
  • Fatigue, easily tired
  • Jaundice, yellow eyes. In newborns with this condition, jaundice may occur from birth.
  • Urine is dark in color, similar to cola or fish sauce.
  • Enlarged liver or spleen
  • Frequent headaches

Factors that trigger hemolysis

  • Certain foods, such as legumes, especially broad beans, blueberries, and red wine
  • Chemicals such as mothballs, camphor, menthol, arsenic.
  • Certain medicines, such as sulfa antibiotics, quinolones, aspirin, malaria medicines, anticonvulsants, and some heart medicines
  • Various infections such as hepatitis, dengue fever, and the common cold.

How should people with this condition behave?

  • Avoid buying medicines or supplements to take yourself.
  • Always inform your doctor and pharmacist if you have G6PD deficiency.
  • Avoid eating foods that stimulate red blood cells to break down.
  • Avoid contact with certain chemicals.
  • Stay healthy avoid infection
  • When you have a fever, you should look for pale yellow symptoms. Notice the color of the urine. and should immediately see a doctor for treatment
  • Avoid various conditions that causes stress or exercising too intensely